骨桥蛋白与糖尿病

The Study Progress of OPN in Diabetes

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摘要骨桥蛋白(osteopontin,OPN)是一种磷酸化糖蛋白,其在不同的生理和病理情况中具有多种功能,包括细胞介导的免疫、炎症进程和动脉粥样硬化的形成等.近年来,越来越多的研究显示,在糖尿病及其并发症中,OPN水平上调.对OPN在糖尿病方面的研究作一综述. Osteopontin(OPN)is a phosphorylated acidic glycoprotein that displays several functions in different physiological and pathological processes,including cell-mediated immunity,inflammatory proceses and progression of atherosclerosis.Recently more and more studies show OPN is upregulated in the diabetes and its complication.This article reviews these researches of OPN in diabetes.

作者张娴宋滇平

机构地区昆明医学院第一附属医院糖尿病科

出处《昆明医科大学学报》 CAS 2009年第S2期162-165,共4页 Journal of Kunming Medical University

关键词骨桥蛋白糖尿病血管病变 Osteopontin Diabetes Vascular pathological changes

分类号 R587.1 [医药卫生—内分泌]

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骨桥蛋白与糖尿病

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