摘要
目的检测胃癌组织中EB病毒的感染情况,以分析EB病毒感染与胃癌的相关性。方法应用聚合酶链反应PCR-Southem技术检测40例胃癌组织和相应癌旁组织中EBV DNA。结果40例胃癌组织中有7例EB病毒感染,阳性率为17.5%,而相应癌旁组织中均未检测到EB病毒感染,二者有显著性差异(P<0.01)。结论EB病毒感染与胃癌的发生有一定的相关性。
Objective To investigate the relationship between Epstein-Barr virus(EBV) and gastric carcinoma.Method The 40 specimens of gastric carcinoma tissues and 40 specimens of corresponding tissues adjacent to the gastric carcinoma were tested for EBV DNA genome by chain reaction(PCR)-Southern blotting.Results EBV was detected in 11(17.5%) gastric carcinoma,but absent in the corresponding adjacent tissues of gastric carcinomas.The difference between the two groups was significant(P<0.01).Conclusion EBV infection is associated with the pathogenesis of gastric carcinomas.
出处
《医学检验与临床》
2008年第1期34-35,共2页
Medical Laboratory Science and Clinics
关键词
EB病毒
胃癌
Epstein-Barrvirus
Gastric carcinoma
