血清载脂蛋白A1和B检测对早期诊断肾脏病继发心血管合并症的价值

Study of Apo - Al and Apo - B in Serum for the Early Diagnosis of Nephritic Secondary Arterosclerosis Cardiovascular Complication

目的 为探讨肾脏病患者继发动脉粥样硬化性心血管合并症的早期诊断。方法用免疫透射比浊法测定尚未出现心血管合并症的48例肾脏病患者和50例健康人(对照组)的血清aopA1和apoB的含量。结果 对照组与患者组结果t检验,除女性组apoB差异无显著意义外,其余各组的各项指标差异均有显著意义(P<0.05)。结论 通过apoA1、apoB的检测发现在肾脏病早期患者体内已具备了心血管合并症的生化基础,提示在治疗肾脏病的同时,应注意早期诊断和防治心血管合并症。

Objective To study the early diagnosis of nephritic secondary arterosclerosis cardiovascular complication. Methods 48 kidney disease patients,who didn' t appear cardiovascular complication yet,and 50 heathy people(contrast team) .The contents of their apoAl and apoB in the serum were determined with immunotransmission turbidimetric method. Results The contents of contrast team s apoAl and apoB to patients team had significant differences except the apoB in females of both teams(P< 0.05) .Conclusion We found that the early nephritic patients had the biochemical disease base apoAl and apoB for cardiovascular complication. This prompts us early diagnosis and presention against cardiovascular compilation while curing the kidney disease.