洁阴Ⅰ号联合抗生素治疗女性顽固性非淋菌性尿道炎、宫颈炎的疗效观察

Jieyin 1 in the treatment of persistent nongonococcal urethritis and cervicitis in female patients

目的观察洁阴Ⅰ号联合抗生素治疗女性顽固性非淋茵性尿道炎、宫颈炎的效果。方法 100例病人被随机分为观察组和对照组。对照组:常规给米诺环素或门冬氨酸阿奇霉素治疗。观察组:在上述治疗的同时加用洁阴Ⅰ号100ml加热后先熏后洗外阴部20分钟,每日2次,连用7天,为一疗程;洁阴Ⅰ号50ml,冲洗阴道,每日2次,连用7天,为一疗程。观察两组病人治疗前后的症状体征变化,一疗程结束后重新采集尿道或宫颈分泌物做解脲支原体培养、沙眼衣原体检测。结果 一疗程结束后,观察组治愈率为58％,总有效率为94％,均高于对照组的32％和46％(均P<0.01)。结论 洁阴Ⅰ号联合抗生素治疗女性顽固性非淋茵性尿道炎、宫颈炎的效果优于单用抗生素。

Objective To observe the therapeutic results of Jieying I for persistent nongonococcal urethritis and cer-vicitis in female patients. Methods 100 cases were randomly divided into two groups. 50 patients in the control group were treated with minocycline or azithromycin. 50 patients in the treated group were treated with minocycline (or azithromycin)and Jieyin I . In the treated patients,vulvae were fumigated,and then washed with Jieyin I 100ml,twice a day for seven days. At the same time vaginal douche were performed with Jieyin I 50ml,twice a day for seven days. The patient's clinical changes after treatment were observed. Mycoplasma culture and chlamydia antigen detection were done in the end of seven day's treatment. Result After seven day's treatment,the cure rate and effective rat were respectively higher in the treated group than in the control group(P<0. 01,P<0. 01). Conclusion Jieyin I have better therapeutic effects for persistent nongonococcal urethritis and cervicitis in female patients.