新生儿呼吸机相关性肺炎的临床探讨

Clinical analysis of ventilator - associated pneumonia in neonate.

为探讨新生儿呼吸机相关性肺炎(ventilator-associated pneumonia,VAP)的病原学和预防措施,对126例机械通气患儿进行回顾性分析。结果显示,126例中发生VAP 53例,感染率42.1％,病死率为15.1％,产超β-内酰胺酶菌感染占首位,葡萄球菌次之,铜绿假单胞菌位居第三。提示VAP治疗中应根据呼吸道分泌物培养结果选择敏感抗生素,尽可能缩短机械通气时间、及时更换呼吸机管道等可减少VAP的发生。

To explore the pathogens and the prophylatic methods of ventilator- associated pneumonia in neonates,clinical information of 126 infants ventilated in the neonatal intensive care unit were analyed.Among 126 cases,VAP were diagnosed in 53 (42.1%) patients, 8 patients died (about 11.3%). The three leading bacteria colonized in pulmonary were Staphylococcus, Klebsiella and Pseudomonas aeruginosa. The concolusion is that the treatment of VAP shoud according to the pathogens, making venriktion treatment as shorter as possible and chaning respiratory tubes timely could reduce the incidence of VAP.