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环境内分泌干扰物对女性生殖健康影响的研究进展 被引量:14

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摘要 环境化学物对人类健康和生态环境影响一直是各国科学家和公众的关注焦点。近年发现它们除有致癌、致突变、致畸等作用,可能也干扰体内激素,引起内分泌紊乱,而且有些效应的化合物被统称为环境内分泌干扰物(EEDs)。EEDs与女性生殖健康关系非常密切。EEDs可通过模拟或拮抗内源性激素,影响内源性激素的合成、代谢和生物利用度等干扰生殖内分泌系统,与不良妊娠结局和妊娠并发症、子宫内膜异位症、卵巢早衰、生殖系统肿瘤、性早熟、月经紊乱等发生有一定的关系。
作者 朱珠 刘嘉茵
出处 《国外医学(妇产科学分册)》 2004年第3期179-182,共4页 Foreign Medical Sciences(Obstet Gynecol Fascicle)
基金 国家科技部重点973项目(2002CB512908)资助
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