抗菌素对不稳定型心绞痛病人缓解症状的影响

Effects of Antibiotics on Remission of Unstable Angina Pectoris

目的 检测C反应蛋白 (CRP)在冠心病不稳定型心绞痛病人应用抗菌素抗炎治疗中的变化及对治疗结果的影响。方法 72例按WHO的分类[1 ] 属冠心病不稳定型心绞痛患者随机分成二组 (n =3 6)。一组 (治疗组 )按常规 +抗菌素抗炎治疗 ,另一组 (对照组 )按常规治疗。比较两组病人治疗前后CRP的变化及对患者治疗结果的影响。结果 CRP在所有入组的心绞痛病人中均有不同程度的升高 ,加用抗菌素抗炎治疗后的心绞痛患者比不加用者CRP数值下降快 ,心绞痛症状缓解快 ,心肌酶指标恢复正常快。

Objectives To find the change of the concentration of C-Reactive Protein (CRP) in the blood of unstable angina patients before and after treatment with antibiotics, and it's relationship to the prognosis. Methods 72 patients (WHO Classification) were divided into 2 groups (n=36) randomly. Observed group received routine treatment and antibiotic treatment. Control group was received routine treatment only. We observed the change of CRP concentration before and after treatment, and compared the curative effect of control group with observed group. Results CRP concentration is higher than normal in all angina patients before treatment. During the treatment, the CRP concentrations of observed group decrease more rapidly than control group. The symptoms of angina and the cardiac enzymes of observed group recovered faster than control group. Conclusions Routine treatment associate with antibiotic can speed up the recover of angina.