Formal Synthesis of (+)-Altholactone by Stereoselective Epoxidation Using Magnesium Monoperoxyphthalate (MMPP)

Formal Synthesis of (+)-Altholactone by Stereoselective Epoxidation Using Magnesium Monoperoxyphthalate (MMPP)

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摘要 Synthesis of (+)-altholactone has been achieved starting from L-tartaric acid using (2S, 3R,4R,5R)-2-hydroxymethyl-3,4-bis(memoxymethoxy)-5-phenyltetrahydrofuran as key intermediate. The key epoxy ring was introduced by monoperoxyphthalate (MMPP) in high stereoselectivity (8.4:1). Synthesis of (+)-altholactone has been achieved starting from L-tartaric acid using (2S, 3R,4R,5R)-2-hydroxymethyl-3,4-bis(memoxymethoxy)-5-phenyltetrahydrofuran as key intermediate. The key epoxy ring was introduced by monoperoxyphthalate (MMPP) in high stereoselectivity (8.4:1).

作者李加尧王志勤赵刚滕尚军丁渝

出处《Chinese Journal of Chemistry》 SCIE CAS CSCD 2002年第11期1415-1420,1133,共6页 中国化学（英文版）

关键词 magnesium monoperoxyphthalate stereoselective epoxidation (+)-altholactone magnesium monoperoxyphthalate stereoselective epoxidation (+)-altholactone

分类号 O621.25 [理学—有机化学]

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Chinese Journal of Chemistry

2002年第11期

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Formal Synthesis of (+)-Altholactone by Stereoselective Epoxidation Using Magnesium Monoperoxyphthalate (MMPP)

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