2Montague CT,Faroqi IS,Whitehead JP,et al.Congenital leptindeficiency is associated with severe early-onset obesity in humans. Nature . 1997
3Beck B,Kozak R,Strieker KA,et al.Neuropeptide Y release in the paraventricular nucleus of Long-Evans rats treated with leptin. Biochemical and Biophysical Research Communications . 1998
4Willet WC,Dietz WH,Colditz GA.Guidelines for healthy weight. The New England Journal of Medicine . 1999
5Valcavi R,Aini M,Peino R,et al.Influence of thyroid status on serum immunoreactive leptin levels. The Journal of Clinical Endocrinology . 1997
6Artaglia L,Dembski M,Wang X,et al.Identification and expression cloning of a leptin receptor. Cell . 1995
7Zhang Y,Proenca R,Mafei M,et al.Positional cloning of the mouseobese gene and its human homologue. Nature . 1994
8Grottoli S,Procopio M,Maccario M,et al.In obesity glucose load loses its early inhibitory, but maintains its late stimulatory effect on somatotrope secretion. The Journal of Clinical Endocrinology . 1997
9Chua SC,Chung WK,Wu P,et al.Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor. Science . 1996
10Clement K,Cabrol S,Pelloux V,et al.Indication for linkage of thehuman OB gene region with extreme obesity. Diabetes . 1996