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Study on the Relationship between Plasma Homocysteine and Acute Cerebral Vascular Disease 被引量:11

Study on the Relationship between Plasma Homocysteine and Acute Cerebral Vascular Disease
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摘要 The levels of plasma homocysteine were determined by using high-performance liquid chromatographic method. It was found that plasma homocysteine levels were significantly higher in the patients with stroke than that in the controls. There was no correlation between plasma homocys- teine levels and hypertension, smoking, concentrations of blood glucose or hypertriglyceridesemia. It was suggested that hyperhomocysteinemia may be an independent risk factor for acute cerebral vascu- lar disease. The levels of plasma homocysteine were determined by using high-performance liquid chromatographic method. It was found that plasma homocysteine levels were significantly higher in the patients with stroke than that in the controls. There was no correlation between plasma homocys- teine levels and hypertension, smoking, concentrations of blood glucose or hypertriglyceridesemia. It was suggested that hyperhomocysteinemia may be an independent risk factor for acute cerebral vascu- lar disease.
出处 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2000年第4期330-331,共2页 华中科技大学学报(医学英德文版)
关键词 HOMOCYSTEINE cerebrovascular disease high-performance liquid chromatography homocysteine cerebrovascular disease high-performance liquid chromatography
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参考文献4

  • 1McCully K S.Vascular pathology of homocysteinemia:implications for the pathogenesis of arteriosclerosis[].American Journal of Pathology.1969
  • 2Tsai J C,Perrella M A,Yoshizumi M et al.Promotionof vascular smooth muscle cell growth by homocysteine:a link to atherosclerosis[].Proceedings of the National Academy of Sciences of the United States of America.1994
  • 3Tsai M Y,Garg U,Key N S et al.Molecular and bio-chemical approaches in the identification of heterozgotesfor homocysteinuria[].Atherosclerosis.1996
  • 4Jacobsen D W,Gatautis V J,Green R et al.RapidHPLC determination of total homocysteine and other thi-ols in serum and plasma: sex differences and correlationwith cobalamin and folate concentrations in healthy sub-jects[].Clinical Chemistry.1994

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