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Bacterially produced human B7-1 protein encompassing its complete extracellular domain maintains its costimulatory activity in vitro 被引量:3

Bacterially produced human B7 1 protein encompassing its complete extracellular domain maintains its costimulatory activity in vitro
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出处 《Chinese Medical Journal》 SCIE CAS CSCD 2000年第8期42-47,共6页 中华医学杂志(英文版)
基金 thegrantsfromtheNationalNaturalScienceFoundationofChina !(No 39470 2 93)
关键词 human B7 1 · B7 1 immunoglobulin domain · T lymphocyte activation human B7 1 · B7 1 immunoglobulin domain · T lymphocyte activation
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参考文献18

  • 1Chen L,Ashe A,Brady WA,et al.Costimulation of antitumor immunity by the B7 counter-receptor for the T lymphocyte molecule CD28 and CTLA-4. Cell . 1992
  • 2Brunet JF,Denizot F,Luciani MF,et al.A new member of the immunoglobulin super family CTLA-4. Nature . 1987
  • 3Linsley PS,Brady W,Grosmaire L,et al.CTLA-4 is a second receptor for B cell activation antigen B7. The Journal of Experimental Medicine . 1991
  • 4Zheng P,Wu Y,Guo Y,et al.B7-CTLA-4 interaction enhances both production of antitumor cytotoxic T lymphocytes and resistance to tumor challenge. Proceedings of the National Academy of Sciences of the United States of America . 1998
  • 5Lenschow DJ,Zheng Y,Thistlethwaite JR,et al.Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA-4 Ig. Science . 1992
  • 6Linsley PS,Brady W,Grosmaire L,et al.Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation. The Journal of Experimental Medicine . 1991
  • 7Freeman GJ,Freedman AS,Segil JM,et al.B7 a new member of the Ig superfamily with unique expression on activated and neoplastic B cells. J Immunol . 1989
  • 8Inobe M,Linsley PS,Ledbetter JA,et al.Identification of an alternatively spliced form of the murine homologue of B7. Biochemical and Biophysical Research Communications . 1994
  • 9Guo Y,Wu Y,Kong X,et al.Identification of conserved amino acids in murine B7-1 IgV domain critical for CTLA-4/CD28: B7 interaction by site-directed mutagenesis: a novel structural model of the binding site. Molecular Immunology . 1998
  • 10Milich D,Linsley PS,Hughes JL,et al.Soluble CTLA-4 can suppress autoantibody production and elicit long term responsiveness in a novel transgenic model. J Immunol . 1994

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