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低强度脉冲超声在骨折愈合中的作用 被引量:2

Effects of low-intensity pulsed ultrasound on fracture healing
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摘要 大量的基础与临床研究表明低强度脉冲超声在生物学及生物力学水平上优化了骨折的愈合过程,并为之提供了一 个理想的修复环境,从而不仅可以促进骨折的愈合,而且可以提高骨折的愈合率;不仅可以促进新鲜骨折的愈合,而且能促进 骨折延迟愈合以及骨不连的愈合。本文回顾了低强度脉冲超声对骨折愈合促进作用的实验及临床研究,探讨其作用机制,并 对低强度脉冲超声的临床应用前景作一展望。 Many basic and clinical studies have showed that through a variety of biological and biophysical mechanisms, low-intensity pulsed ultrasound improves the fracture healing and provides an ideal repairing environment.Thus,it can not only accelerate the healing of fractures,but also enhance the healing rates;not only accelerate the healing of fresh fractures, but also the healing of delayed unions and nonunions.This review elaborates on the effects of low-intensity pulsed ultrasound on the healing of fractures,its mechanisms and its prospective applications. [
作者 王琪 苟三怀
出处 《第二军医大学学报》 CAS CSCD 北大核心 2004年第6期673-675,共3页 Academic Journal of Second Military Medical University
关键词 低强度脉冲超声 骨折愈合 骨折延迟愈合 骨不连 low-intensity pulsed ultrasound fracture healing delayed union nonunions
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参考文献25

  • 1[1]Kaufman JJ,Einhorn TA. Ultrasound assessment of bone[J].J Bone Miner Res,1993,8(3):517-525.
  • 2[2]Moed BR,Kim EC,van Holsbeeck M,et al. Ultrasound for the early diagnosis of tibial fracture healing after static inter locked nailing without reaming: histologic correlation using a canine model[J ]. J Orthop Trauma, 1998,12 (1): 200-205.
  • 3[3]Azuma Y,Ito M,Harada Y,et al. Low-intensity pulsed ultrasound accelerates rat femoral fracture healing by acting on the various cellular reactions in the fracture callus [J]. J Bone Miner Res, 2001,16(4) :671-680.
  • 4[4]Khan SN,Bostrom M,Lane JM. Bone growth factors[J]. Orthop Clin North Am, 2000,31 (2) :375-387.
  • 5[5]Clinton R,Mark B, Ruaby JP,et al. The use of low-intensity ultrasound to accelerate the healing of fractures [J]. JBJS,2001,83A(2) :259-270.
  • 6[6]Mayr E,Laule A,Suger G,et al. Low-intensity pulsed ultrasound accelerates bone maturation in distraction osteogenesis in rabbits [J].J Bone Joint Surg (Br), 2000, 82 (6): 1077-1082.
  • 7[7]Glazer PA,Hellmann MR,Lotz JC,et al. Use of ultrasound in spinal arthrodesis. A rabbit model [J]. Spine, 1998, 23 (10):1142-1148.
  • 8[8]Cook SD,Ryaby JP,McCabe J,et al. Acceleration of tibia and distal radius fracture healing in patients who smoke[J]. Clin Orthop, 1997,337 (1): 198-207.
  • 9[9]Kristiansen TK,Ryaby JP, McCabe J,et al. Accelerated healing of distal radial fractures with the use of specific ,low-intensity ultrasound. A multicenter, prospective, randomized,double-blind, placebo-controlled study [J]. J Bone Joint Surg (Am), 1997,79(7): 961-973.
  • 10[10]Mayr E, Rutzki MM, Rudzki M, et al. Does low-intensity pulsed ultrasound speed healing of scaphoid fractures[J]?Handchir Mikrochir Plast Chir, 2000,32 (1): 115-122.

同被引文献23

  • 1张超,梁国穗,张颖恺,胡蕴玉,阮狄克.低强度脉冲超声波刺激对人骨髓基质细胞和骨膜细胞生物学效应的影响[J].中华物理医学与康复杂志,2005,27(11):657-660. 被引量:10
  • 2赵明杰,周丰慧,刘斌.超声波中药离子透入促进骨折愈合的实验研究及临床观察[J].广东医学,2006,27(6):788-789. 被引量:10
  • 3王志文,张爱国,袁强,赵文毅,孙丽丽,李曙光.麝香乌龙丸对兔实验骨折BMD、BMC、BMP的作用研究[J].四川中医,2006,24(12):11-12. 被引量:8
  • 4徐琳峰,樊振勇,胡坚勇,纵亚,陈丽娜,傅华洲,顾伟忠.超声中药透入促进大鼠骨折愈合的实验研究[J].中华物理医学与康复杂志,2007,29(7):436-438. 被引量:7
  • 5Shakouri K,Eftekharsadat B,Oskuie MR,et al.Effect of low-intensity pulsed ultrasound on fracture callus mineral density and flexural strength in rabbit tibial fresh fracture.J Orthop Sci.2010;15(2):240-244.
  • 6Lai CH,Chen SC,Chiu LH,et al.Effects of low-intensity pulsed ultrasound,dexamethasone/TGF-beta1 and/or BMP-2 on the transcriptional expression of genes in human mesenchymal stem cells:chondrogenic vs osteogenic differentiation.Ultrasound Med Biol.2010;36(6):1022-1033.
  • 7Parvizi J,Wu CC,Lewallen DG,et al.Low-intensity ultrasound stimulates proteoglycan synthesis in rat chondrocytes by increasing aggrecan gene expression.J Orthop Res.1999;17(4):488-494.
  • 8Rubin C,Bolander M,Ryaby JP,et al.The use of low-intensity ultrasound to accelerate the healing of fractures.J Bone Joint Surg Am.2001;83-A(2):259-270.
  • 9The Ministry of Science and Technology of the People's Republic of China.Guidance Suggestions for the Care and Use of Laboratory Animals.2006-09-30.
  • 10Sun JS,Hong RC,Chang WH,et al.In vitro effects of low-intensity ultrasound stimulation on the bone cells.J Biomed Mater Res.2001;57(3):449-456.

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