5-FU、海藻多糖、黄芪多糖复方抗癌制剂抗肿瘤药理作用的研究

PHARMACOLOGICAL STUDY OF COMPLEX PRESCRIPTION OF 5-FU AND POLYSACCHARIDES ISOLATED FROM RADIX ASTRAGALI SEU HEDYSARI AND SARGASSUM ON ANTITUMOUR

由５一ＦＵ、海藻多糖、黄芪多糖组成复方抗癌制剂（以下简称复方）。对小鼠体内移植肉瘤（Ｓ１８０）、小鼠肝癌（Ｈ２２）均有显著的抑制作用，与化疗药物５一ＦＵ相比，抑瘤作用增强，毒副作用降低。复方可提高荷瘤小鼠红细胞免疫功能，减轻化疗药物对机体的免疫抑制作用。

Polysaccharides isolated from radix astragali seu hedysari and sargassum exerted antitumor action on human body by activating its immune system. The complex prescription including 5-FU and polysaccharides isolated from radix astragals seu hedysari and sargassum inhibited obviously S180 and H22 in mice, increased the cellular immune fuction and alleviated the effection of chemotherapeutical drugs on human body.