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活性氧与细胞凋亡 被引量:3

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摘要 细胞凋亡(apoptosis)是一种不同于坏死的细胞程序性死亡(programedceldeath)。细胞凋亡时呈现特征性的形态学和生物学改变,包括胞体皱缩,染色质浓缩,DNA非随机断裂,质膜出芽,将细胞分隔成许多大小不一的凋亡小体。正常情况下,通过...
作者 于爱平
出处 《实用医药杂志》 1999年第4期64-65,共2页 Practical Journal of Medicine & Pharmacy
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  • 1周永列,吕亚萍,邱莲女,王文松,林惠君.硝普钠诱导K562细胞凋亡机制的研究[J].中国实验血液学杂志,2005,13(6):983-988. 被引量:5
  • 2米娜,潘秀颉,杨陟华,姚华,朱茂祥.卷烟烟气对机体的氧化损伤[J].环境保护,2007,35(05A):63-65. 被引量:3
  • 3JOSEPH S,RUSSELL D W.分子克隆实验指南[M].第3版.北京:科学出版社,2002:479-483.
  • 4Baglole C J, Bushinsky SM, Garcia TM, et al. Differential induction of apoptosis by cigarette smoke extract in primary human lung fibreblast strainsi implication for emphysema[J]. Am J Physiol Lung Cell Mol Physiol, 2006,291(1): 19-29.
  • 5Jo PC, Choi YK, Choi CY. Cloning and mRNA expression of antioxidant enzymes in the pacific oyster, crassostrea gigas in response to cadmium exposure[J]. Comparative Biochemistry and Physiology,2008,14?(4):460--469.
  • 6Lee E, Choi MK, Youk HJ, et al.5-(4-chlorophenyl)-1-(4- methoxYphenyl)-3-tritluoromethyl-pyrazole acts in a reactive oxygen species-dependent manner to suppress human lung cancer growth[J]. Journal of Cancer Research and Clinical Oncology,2006,132(4):223-233.
  • 7Zhao Z, Francis CE, Welch G, et al. Reduced glutathione prevents nitric oxide-induced apop-tosis in vascular smooth muscle cells[J]. Biochim Biophys Acta, 1997,1359(2): 143-152.
  • 8Ying M, Tu C, Ying H, et al. MSTZ, a flavanone derivative, ,induces human hepatoma cell apoptosis via a reactive oxygen species-and caspase-dependent niitochondrial pathway[J]. Journal of Pharmacology and Experimental Thera- peutics, 2008, 325(3):758-765:
  • 9Goldman R, Moshonov S, Chen X, et al. Crosstalk between elevation of [ Ga^2+], reactive oxygen spesies generation and phospholipase A2 stimulation in a human keratinocyte cell line [J]. Adv Exp Med Biol, 1997,433:41-45.
  • 10Volk T, Hensel M, Kox W. Transient Ga^2+ changes in endothelial cells induced by low dose of reactive oxygen species; role of hydrogen per oxide [ J ]. Mol Cell Biochem, 1997,171 : 11-21.

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