SCE率与肿瘤易患性关系的实验研究

The Experimental Study on the Relationship Between SCE Rate and Tumour Liability

采用微量全血培养法，对10O例恶性肿瘤患者和32例正常人外周血淋巴细胞在自然状态下的SCE率与在微量丝裂霉素（MMC）作用下SCE率进行实验分析。结果：肿瘤患者在自然状态下的SCE率和在MMC作用下的SCE率与正常人比较存在显著差异。说明肿瘤患者染色体稳定性较差，肿瘤易患性较高。

Tace whole blood culture method was used to analyze SCE rates of external blood lym phocyte at natural state and under MMC's action in 100 cases of malignant tumour and 32 normal per sons. The result showed the SCE rate at natural state and MMC action in the patients with tumour had notable difference compared with normal persons, and the rate chromosome aberration in the pa tients with tumour also has notable difference with normal persons. It is indicated that chromosome is not very stable in the patients with tumour wich would lead to the occurrence of tumour.