结石性慢性胆系炎症患者胆汁sIgA的检测及意义

Change of Bile sIgA in Patients with Chronic Calculous Biliary Inflammation

为观察结石性慢性胆系炎症患者手术前后胆汁。sIgA含量变化及意义，利用放射免疫法分别测定术中和术后14天胆总管胆汁sIgA含量。发现胆道术后残余结石患者胆汁中sIgA虽低于术前，但无显著性差异（P＞0．05），而无残余结石患者术后胆汁sIgA显著低于大前和有残余结石患者（P均＜0.01）。表明胆汁sIgA含量随局部炎症发生而增高．局部炎症减轻而降低。故胆汁sIgA的测定可作为胆道术后监测胆道炎症变化及有无残余结合的参考指标。

In order to study bile slgA levets in patients with chronic calculous biliary inflammation, We measured sIgA levels of bile in common bile ducts with radioimmunoassay at intraoperation and the 14th day after operation, and found that postoperative sIgA level of bile in patients with no residual calculuses was lower than that in patients with residual talculuses and the intraoperative average sIgA level. In conclusion,sIgA level of bile can be used to supervise the degree of biliary inflammation at postoperative period. It maybe become a indicator to determine whether a biloty tract remains calculuses after operation.