期刊文献+

转基因家畜的研究及进展

下载PDF
导出
摘要 1980年,Gordon应用显微注射法首次成功地将重组的外源DNA直接注入小鼠受精卵的雄原核中获得了携带外源基因的小鼠。Gordon和Ruddle1981年将带有外源基因的小鼠称为转基因小鼠(tansgenicmice)。“转基因动物”一词也应运而生。动物转基因技术克服了物种之间的生殖隔离,实现了动物物种之间遗传物质的变换和重组。因此,研究转基因家畜在理论和生产应用上都有广阔而诱人的前景,本文就转基家畜研究的方法、现状以及存在的问题和展望进行了综述。
出处 《河北北方学院学报(自然科学版)》 1998年第2期58-63,共6页 Journal of Hebei North University:Natural Science Edition
  • 相关文献

参考文献22

  • 1Gordon JW. et al.Gentic transformation of mouse embryos by microinjection of Purified DNA. Proceedings of the National Academy of Sciences of the United States of America . 1980
  • 2Hyttinen JM. et al.Generation of transgenic dairy cattle from transgene-andalyzed and sexed embryos produced in vitro. Journal of Biotechnology . 1994
  • 3Burdon TG,Wall RJ.Fate of microinjected genes in preimplantation mouse embryos. Molecular Reproduction and Development . 1992
  • 4Anthony WS. et al.Expression of green fluorescence protein in mammalian embryos: A novel reporter gene for the study of transgenesis and embryo development. Theriogenology . 1997
  • 5Clark AJ.Rescuing transgene expression by co-integration. Journal of Biotechnology . 1992
  • 6Bondioli KR. et al.Positive selection of transgenic bovine embryos in culture. Theriogenology . 1996
  • 7Wrigh G. et al.High level expression of active human alpha-1-antitrpsin in the milk of transgenic sheep. Bio Technology .
  • 8Weidle VH. et al.Genes encoding a mouse monoclonal, antibody are expressed in transgenic mice, rabbits and pigs. Gene . 1991
  • 9Simons JP.Alteration of the quality of milk by expression of B-Lactoglobulin in transgenic mice. Nature . 1987
  • 10Voss AK. et al.A comparison of mouse and rabbit embryos for the production of transgenic animals by pronuclei microinjection. Theriogenology . 1990

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部