碳酸锂对血清T3、T4、TSH影响的对照观察

Comparative Observation of Effect of Lithium on Serum Level of T_3、T_4 and TSH

目的：了解锂盐对甲状腺激素水平影响的关系．方法：对29例接受碳酸锂治疗3～9个月的情感性精神障碍患者和25例健康对照者做了血清三碘甲状腺原氨酸（T3）、甲状腺素（T4）和促甲状腺素（TSH）的对照观察．结果：服锂盐组T3（1．02±0．42ng／ml）、T4（50．94±29．09ng／ml）明显低于对照组，TSH（9．20±7．64uIU／ml）明显高于对照组（4．74±4．73uIU／ml）．结论：锂盐对甲状腺激素的影响在接受锂治疗6个月左右尤为显著．

To study the effect of lithium on the level of thyroid hormones in the patients with affective disorder. Method The serum triiodothyronine (T3),thyroxin(T4)and thyroid stimulating hormone (TSH) were resistively tested in 29 patients with affective disorder and 25 normal controls, and were compared between the two groups. Resulta It was found that the patient group had significantly lower serum T3 and T4 level, but higher serum TSH level than those of the control group. Conclasion It suggests that the effect of lithium on serum thyroid hormones is extremely significant in the sixth month of the treatment of lithium.