伴无症状性脑梗塞抑郁症12例自身对照分析

Auto-Control on 12 Cases of Depression Concomitant silent Cerebral Infarction

目的：探讨抑郁症伴发的无症状性脑梗塞（SCI）对抑郁症状发生、发展的影响．方法：选先后两次住我院并伴有SCI的抑郁症患者12例，进行梗塞出现前后自身对照分析．结果抑郁症的特征性症状：如抑郁心境、自杀意念与行为、晨重夕轻、早醒等方面比较差异无显著性（P＞0．05），而焦虑激越、躯体不适主诉、疑病、妄想等方面在伴SCI时显著较高（P＞0．05），治疗剂量则显著低于无SCI时，好转时间也显著延长（P＜0．05）．出院时疗效差异无显著．结论：SCI的存在是加重原有抑郁症状的重要原因之一．

To approach the effect of depression concomitant silent cerebral infarction on the occurence and development of depression. Method An auto-control analysis. Results the results showed that before and after silent cerebral infarction (SCI) occured, the difference. were not significant in depressive symptoms such as depression, suicidal idea and behavior, circadian rythem and early waking etc, but significant in anxiety, complaints of physical uncomfortableness, hypehondrissis and delusion etc. The curative dosage was remarkably lower, and the recovered days were remarkably longer before SCI occured than those of concomitant SCI.But it was not found significant difference in curative effect during discharge time. Conclusion It suggests that SCI is one of the most important factors exacerbating depressive symptoms.