抗结核药栓填塞治疗难治性耐多药肺结核空洞的疗效研究

A study of treatment effects on refractoriness MDR-TB bacuum stuff with antiphthisic stype

目的 探讨抗结核药栓填塞治疗难治性耐多药肺结核空洞的临床疗效。方法 在纤维支气管镜引导下 ,将抗结核药栓定期注入难治性耐多药肺结核空洞内 ,用 X线胸片等方法动态观察变化。结果 治疗组比对照组痰菌阴转率高 ,空洞闭合率高 ,单发空洞、干酪空洞的疗效比多发空洞、纤维空洞的疗效较好。未发现与介入药栓有关的毒副作用。结论 经纤维支气管镜引导灌注抗结核药栓 ,是治疗难治性耐多药肺结核空洞的有效方法 ,无明显毒性反应 。

Objective To assess the effects of treatment on the refractoriness MDR TB vacuum stuff with antiphthisic stype.Methods Under fiberonchoscope guide,injected high effect antiphthisic stype stuff that unti drug tolerant pulmonary tuberculosis to the refractoriness MDR TB vacuum,and contrast observes the trends changes of vacuum with X ray chest radiography. Results The negative ratio of sputum examination for tubercle in therapy group bacillus was higher than control group,and the close ratio of vacuum was also higher in the therapy group than in the control grpup.The therapeutic effects of single,caseous vacuum were better than multiple,fibril vacuum.Conclusion It is an effective method that under fiberonchoscope guide injected antiphthisic stype stuff that unti drug tolerant pulmonary tuberculosis to therapy refractoriness MDR TB vacuum.