江苏省七城市小儿脑性瘫痪的危险因素研究

Risk Factors of Childhood Cerebral Palsy in Seven Citics of Jiangsu Province,China.

目的探讨脑瘫的危险因素,为病因和防治措方叵研究奠定基础。方法1997年5月至6月在苏州等七个县市进行了以人群为基础的1:2病例对照研究。结果脑瘫的危险因素基本分两大类:第一类是产时新生儿期因素。他们与脑瘫的关联程度大并且具有卫生学意义;第二类是产前因素。这类因素与脑瘫关联程度有限,但数目多,人群暴露率高,值得进一步研究。结论进一步进行产前有关因素与产时和新生儿期某些危险因素之间关系的研究,有助于深化认识脑瘫的产前危险因素。

Objective To approach risk factors of cerebral paslsy.Methods A population- based 1:2 matched case-control study was carried out during May to June in 1997 in seven cities of Jiangsu province,China.Results Risk factors associated with childhood cerebral palsy(CP) were summarizd into two basic groups according to the magnitude of their odds ratio(OR):one was factors occurring during and after labor and delivery,they were highly correlated with CP.The other was an- tenatal factors,but their influence was comparitive weak.Conclusion It is helpful to do further study on the relationships among risk factors presented before,during and after delivery for the fur- ther realizing of risk factors of CP.