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感染日本血吸虫小鼠心房特殊颗粒的形态学观察和定量分析 被引量:1

MORPHOLOGIC AND QUANTITATIVE STUDY OF ATRIAL SPECIFIC GRANULES IN MICE INFECTED WITH SCHISTOSOMA JAPONICUM
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摘要 小鼠感染日本血吸虫尾蚴后第28天,右心耳心房特殊颗粒数目显著减少,且多见膜溶解、断裂,半月形排空和颗粒膜与横管膜及肌膜靠近、融合及颗粒向横管腔及肌膜下突出的现象。心肌细胞内线粒体有肿胀、基质变浅及部分嵴断裂现象。感染组小鼠右心耳心房特殊颗粒的体密度(0.0323±0.0029μm3/μm3)、面数密度(0.8647±0.0692μm-2)、数密度(3.2363±0.1114μm-3)及颗粒平均直径(0.2671±0.0207μm)均显著小于对照组的0.0971±0.0127μm3/μm3、1.921±0.1145μm-2、0.2189±0.0866μm-3和0.3108±0.0195μm。本文阐述了日本血吸虫感染后,促进心房特殊颗粒释放增加。 28 days following infection of cercaria of Schistosoma japonicum, the number of atrial specific granules (ASG) in the right auricle of mice was decreased significantly and in some of the granules, the phenomenon of dissolving and breaking of membrane, half moon like excluding, closing and merging of ASG and the membrane of the transverse tube and sarcolemma in the heart muscle cells and protruding of ASG towards the lumen of the transverse tube and sarcolemma were often observed. Many mitochondria in the heart muscle cells showed swelling, shallowing of matrix and breaking of parts of the cristae. The ASG volume density (0 0323±0 029μm 3/μm 3), numerical density on area (0 8647±0 0692μm -2 ), numerical density (3 2363±0 1114μm -3 and mean diameter (0 2671±0 0207μm) in the tested group were respectively less than those (0 0971±0 0127μm 3/μm 3,1 921±0 1145μm -2 ,6 2189±0 0866μm -3 ,0 3108±0 0195μm) in the control group. The relationship between ASG and the Schistosoma japonicum infection was briefly discussed.
出处 《中国组织化学与细胞化学杂志》 CAS CSCD 1998年第1期92-95,共4页 Chinese Journal of Histochemistry and Cytochemistry
关键词 日本血吸虫 心房特殊颗粒 免疫组织化学 Schiotosoma japonicum, Atrial specific granules
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参考文献3

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  • 1江应安,严少南.晚期血吸虫病患者血浆心钠素水平的检测及意义[J].中华内科杂志,1993,32(9):613-615. 被引量:1
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