数量性状基因座的动态定位策略

Strategy of Dynamic Mapping of Quantitative Trait Loci

分子标记辅助数量性状基因（QTL）定位和效应分析技术为深入研究数量性状的遗传基础提供了一个有力手段．但目前的QTL定位策略是静态的，只估计各QTL在某观察时刻的累积效应，无法了解QTL的表达动态．本文提出一种新的QTL定位策略，称为“动态定位”，能够揭示QTI表达的动态过程，并能极大地提高QTL定位的统计功效.

The technique of molecular marker-mediated mapping and effect analysis of quantitative trait loci（QTLs）has supplied a powerful tool for deep research of the genetic basis of quantitative traits.At present,however,the strategy of QTL mapping is static,it only estimates the cumulative effects of QTLs at a moment of observation and cannot investigate the expression dynamics of QTLS.In this paper,a new QTL mapping strategy Called dynamic mapping is pro-posed,which can reveal the dynamic process of QTL expression and considerably increase the sta-tistical power of QTL mapping as well.