以充气背心为主体的新型双泵复苏术血流动力学研究(2)

“Double Pump”Cardiopulmonary Resuscitation:The Hemodynamic Study of the Inflational VEST with External Counterpulsation(Ⅱ)

以充气背心为主体的新型双泵复苏术（ＶＤＶＥＳＴ－ＣＰＲ）能改善冠脉有效灌注压（ＣＰＰ），观测其复苏效果随时间变化．以ＩＢＭＰＣ３８６为控制主机的多功能复苏装置，在８条犬心室颤动３０ｓ后随机地实施充气背心复苏术（ＶＥＳＴ－ＣＰＲ）及ＶＤＶＥＳＴ－ＣＰＲ３０ｍｉｎ，每隔５ｍｉｎ观测一次，自身对照设计．结果：整个实验中，ＶＤＶＥＳＴ－ＣＰＲ较ＶＥＳＴ－ＣＰＲ显著升高主动脉和右房的舒张压（Ｐ＜０．０１）．主动脉舒张压升高程度较右房舒张压大，ＣＰＰ显著性升高（Ｐ＜０．０１）．虽然随复苏时间延长，复苏效果有所下降，但是ＶＤＶＥＳＴ－ＣＰＲ始终优于ＶＥＳＴ－ＣＰＲ．ＶＤＶＥＳＴ－ＣＰＲ３０ｍｉｎ的复苏中，血流动力学效果优于ＶＥＳＴ－ＣＰＲ．

It has been reported that a novel CPR named as VDVEST-CPR which was inflation vest assisted with external (CPP).The between hemodynamic effect of VDVEST-CPR and resuscitation time was studied.Methods:After 30s of ventricular fibrillation both VDVEST-CPR and VEST-CPR were executed in random order on each of 8 d and alternated in 90 s interval.Two CPRs were repeated per 5 min for 30 min.statistical analysis used by paired-t test and linear regression.Results:During the experiment of 30 min the diastolic pressure of aorta (Pao) and right atrium (Pra) in VDVEST-CPRR were significantly higher than in VEST-CPR (P< 0.01), but the increment of diastolic Pao was greater than that of diastolic Pra,so that CPP were improved significantly in VDVEST-CPR (P<0.01).Although CPP was decrease gradually,CPP of VDVEST-CPR was greater than VEST-CPR.Conclusion:The hemodynamic effect of VDVEST-CPR was superior to VEST-CPR in the canine experiment.