发凝集试验快速检测肾综合征出血热病毒抗原的实验诊断

Experimental study of carbon agglutination test for the rapid diagnosis of hemorrhagic fever renal syndrom virus antigen

应用肾综合征出血热病毒的单克隆抗体A25-1、A19和A5等量混合液标记活性炭，然后与肾综合征出血热病毒的陈株、湖北珠巨细胞病毒和呼吸合胞病毒作凝集试验。结果仅陈株和湖北株产生特异性凝集，而巨细胞病毒和呼吸合胞病毒不产生凝集。阻断试验的结果为阴性，说明炭凝集试验．可以用于肾综合征出血热的快速诊断。

The activated carbon labeled HFRSV mixed monoclone antibody was employed to perform carbon agglutination test (CAT) together with HFRSV Chen strain, Hubei strain,CMV and RSV. The results showed that agglutination appeared only in HFRSV, not in other viruses. It indicated that CAT may be more helpfu1 for the diagnosis of HFRS.