应用免疫斑点法检测恙虫病立克次体抗体

Detection of antibody to rickettsia tsutsugamushi by immunodot blot

应用免疫斑点法检测恙虫病立克次体抗体，与间接免疫荧光试验比较，免疫斑点试验的敏感性和特异性分别为96．9％和956％，该方法简便，不需要仪器设备，适合基层单位使用及大面积血清流行病学调查。

Antibodies to rickettsia tsutsugamushi detected by immunodot blot (IDB). IDB showed no significant differences with indirect immunofluorescent test (IIF) in detection of the IgG antibody. The sensitivity and specificity of the method were 96. 9% and 95. 6% respectively in comparison with IIF' With easy performance, it may be applicable for small hospltal and large scale epidemic investigation of tsutsugamushi disease',