妊娠高血压综合征患者血清尿酸水平测定的意义

Clinical Significance of Serum Uric Acid Level in Patients with Pregnancy-induced Hypertension Syndrome

目的 研究妊娠高血压综合征患者血清尿酸水平的改变及其临床意义。方法 检测 62例本病患者及 48例正常妊娠妇女的血清尿酸水平。结果 患者血清尿酸水平高于正常妊娠妇女 (P <0 .0 1) ,患者血清尿酸水平高者其新生儿体重低 (P <0 .0 1)、围生儿病死率高 (P <0 .0 1)。结论 妊高征患者的血清尿酸水平与新生儿体重、围产儿病死率相关 ,可以通过监测妊高征患者的血清尿酸水平来估计妊娠的预后。

Objective To investigate the changes of the serum uric acid levels in patients with pregnancy induced hypertension (PIH) and its clinical significance. Methods The serum uric acid levels were detected in 62 patients with PIH and 48 normal pregnant women. Results The serum uric acid levels in patients with PIH were significantly higher than those of normal pregnant women (P<0.01). And their newborns' weight was lower than the newborns of normal pregnant women (P<0.01). The mortality of newborns was higher than newborns of normal pregnant women (P<0.01). Conclusions The newborn's weight and the mortality of infants were related to the serum uric acid levels in patients with PIH. The patients' prognosis could be evaluated by measuring their serum uric acid levels.