新生儿机械通气相关性肺炎细菌培养结果分析

Analysis of Bacterial Culture in Newborn With Ventilator Associated Pneumonia

目的 探讨新生儿机械通气并发肺炎的细菌种类和药敏情况以指导临床用药。方法 选取住院病人中机械通气并发新生儿肺炎病人 2 4例 ,采用无菌操作用一次性吸痰管吸气管内分泌物 ,并对痰细菌培养结果进行分析。结果 2 4例中大部分为革兰氏染色阴性菌 ,其中大肠埃希菌最多 ,共 11例 ( 4 5 .83 % ) ,其次为肺炎克雷白氏菌和芳香沙雷氏菌 ,各 5例 ( 16.67% )。结论革兰氏阴性菌是机械通气合并新生儿肺炎的主要病原 ,其中主要是大肠埃希菌 ,对大部分抗生素耐药。而头孢他啶、泰能、环丙沙星、丁胺卡那霉素、氨曲南耐药率低 ,可以首先选用。

Objective To investigate the species of bacteria in newborns with ventilator associated pneumonia and the result of drug susceptibility, so as to guide the clinical usage of antibiotics. Methods The secretion of trachea was absorbed with one-off pipe and was culture for bacteria in 24 newborns with ventilator associated pneumonia. The results of bacterial culture were analyzed. Results The main pathogens were Gram-negative bacteria in 24 patients, Escherichia coli was detected in 11 patients (45.83%). K. pneumoniae and S. marcescens were detected in 5 patients separately (16.67%). Conclusions The main pathogens were Gram-negative bacteria. E. coli was the main bacteria and it was resistant to many antibiotic. But it was sensitive to tienam, ciprofloxacin, amikacin, aztreonam.