245例肝硬变患者肝内血管病变的形态观察

MORPHOLOGICAL OBSERVATION OF INTRAHEPATIC VESSEL DAMAGE IN 245 CASES OF CIRRHOTIC PATIENTS

用本文制定的血管病变评定标准,对245例肝硬变标本进行组化、免疫组化及电镜观察,结果表明,本组病例皆有肝内静脉血管的炎症、损伤、增生及阻塞病变,多伴随肝窦毛细血管化,肝窦扩张及阻塞表现,Ⅳ型胶原、FN、LN及弹力纤维也增多,从而导致肝血供不良。

To observed the histochemical, immtmohistochemical stain and electron microscope of 245cases of cirrhosis samples, We used a vessel damage evaluing standard we developed.The results showed that all the cases in this group had inflamatioruinjury.proliferation and obstruction in hepatic vessel.And most were associated with capillarization-v dilation and obstruction of hepatic simusoids.The IV-type collagen, fibroiifctm( FN), laminin(IN) and elastic fiber also increased.All of these could result in hepatic ischemia.