血浆置换疗法在风湿病中的临床应用研究

CLINICAL STUDY OF PLASMA EXCHANGE IN THE RHEUMATIC DISEASES

应用自动血浆分离器对133例风湿病进行463人次血浆置换（PE），取得了显著疗效，显效66．91％，有效28．5％，无效4．51％，总有效率95．48％．在PE时观察到，在PE前病情活动期血清SIL－2R、SIL－6水平明显升高，并且SIL－2R与血沉呈正相关（r=0．540，P＜0．10）。研究指示：SIL－2R、SIL－6水平升高可作为风湿病患者病情活动及恶化的观察指标。

Article reported 133 cases suffering from rheumatic disease. The patients had been treated withplasma exchange (PE) and achived remakable effect. The rema kable effective rate,the effective rate and the totaleffective rate after therapy were 66. 91 %, 28. 5 %, 95' 48 %, respectively. We also observed that the levels of SIL-2Rand SIL-6 increased singnificantly in the patients before the PE. The levels of SIL-2R had positive relation with thelevel of ESR. The study suggests that the increased concetration of SIL-2R and SIL-6 can serve an indicator ofrheumatic disease activation and/or exacerbation.