High　Efficiency　Gene Transfer　to　Autologous　Rabbit　Jugular　Vein　Grafts　Using　Recombinant　Adenovirus─Transferrin／Polylysine─D

HighEfficiencyGeneTransfertoAutologousRabbitJugularVeinGraftsUsingRecombinantAdenovirus┐Transferrin/Polylysine┐DNAComplexes

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摘要 Thesedatashowthathigh-efficientgenetransductioncanbeachievedinautologousveingraftsusingadenovirus-transferin/polylysine-DNAcomplexes.Thismethodoferssomeadvantagesoverrecombinantretrovirusofadenovirusvectors.Exvivogenetherapyofveingraftsmayreducegraftocclusionbytheintroductionandhighlevelexpresionofantithromboticand/orantiproliferativegenes. Thesedatashowthathigh-efficientgenetransductioncanbeachievedinautologousveingraftsusingadenovirus-transferin/polylysine-DNAcomplexes.Thismethodoferssomeadvantagesoverrecombinantretrovirusofadenovirusvectors.Exvivogenetherapyofveingraftsmayreducegraftocclusionbytheintroductionandhighlevelexpresionofantithromboticand/orantiproliferativegenes.

作者刘国庆朱宇蔡海江

出处《The Journal of Biomedical Research》 CAS 1996年第1期2-6,22,共6页 生物医学研究杂志（英文版）

关键词 autologousveingrafts GENEEXPRESSION GENETRANSFER ADENOVIRUS Β-GALACTOSIDASE autologousveingrafts geneexpression genetransfer adenovirus β-galactosidase

分类号 R394.3 [医药卫生—医学遗传学]

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The Journal of Biomedical Research

1996年第1期

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High　Efficiency　Gene Transfer　to　Autologous　Rabbit　Jugular　Vein　Grafts　Using　Recombinant　Adenovirus─Transferrin／Polylysine─D

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High Efficiency Gene Transfer to Autologous Rabbit Jugular Vein Grafts Using Recombinant Adenovirus─Transferrin／Polylysine─D

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High　Efficiency　Gene Transfer　to　Autologous　Rabbit　Jugular　Vein　Grafts　Using　Recombinant　Adenovirus─Transferrin／Polylysine─D