乙型肝炎患者血清、唾液及尿液中沙眼衣原体的检测

Detection of Chlamydia Trachomatis in Sera, Saliva and Urine of Patients with Hepatitis B

本文采用PCR法对40例乙型肝炎患者血清、唾液及尿液进行沙眼衣原体(CT)DNA检测,设正常对照30例。结果显示:乙型肝炎患者的CT感染总阳性率为40.0％(16/40),其中血液为15.0%(6/40),唾液为20.0%(8/4O),尿液为17.5%(7/40):正常人总阳性率为10.0％(3/30),其中血液6.7％(2/30),唾液3.3％(1/30),尿液10.0％(3/30),显著低于乙型肝炎组(P<0.05)。CT感染主要表现为隐性感染和携带者。在肝炎患者尿、唾液和血液中查到CT,说明其传播是多途径的,在接吻、输血及性生活中可能传播CT。CT感染在乙型肝炎患者中的分布主要见于慢性肝炎和肝硬变,这可能与患者细胞免疫功能低下有关。

The Chlamydia trachomatis (CT) in sera,Saliva and urine of 40 patients with hepatitis B and of 30 healthy persons were de-tected by PCR method. The results showed that the CT prevalence in these hepatitis B patients was as high as 40%,while that of healthy persons was only 10%. Subclinical patients and carriers were the main menifestations of CT infection. Our results also in-dicated that CT might be transmitted through multiple ways.