南京地区消化科医护人员中幽门螺杆菌感染的流行病学调查

Infetion of helicobacter pyloi(HP)in gastroenterology staff in Nanjing

以检测末梢血抗幽门螺杆菌（ＨＰ）ＩｇＧ的方法，调查了南京地区１０２名消化科医护人员和１３０名非消化科医护人员的ＨＰ感染状况，发现前者光密度值（０．７１±０．２９），非常显著地高于后者（０．４９±０．２８）（Ｐ＜０．００５）；在消化科或内镜室工作＜５年、５～１０年、＞１０年的三组人群之间不存在显著性差异；消化科医师与护士比较（Ｐ＞０．０５），内镜人员与普通消化科人员比较（Ｐ＞０．０５），亦未显示显著差异。作者认为：①消化科人员在医患接触中获得ＨＰ感染的危险高于医院内其他人群；②从事消化科临床工作５年之内获得ＨＰ感染的危险度即已达到饱和值水平；③使用手套可能会降低医患接触过程中ＨＰ感染的传播。

Methods Two hundreds and thirty-two subjects working in six hospitals in Nanjing were investigated,in whom there were 102 gastroenterologists and gastroenterology nurses(G group),and 130 nongastroenterology practioners(NG group).Each of the subjects was required to complete a questionaire to determine sex,the number of years they had been working during endoscopy procedures,andwhether they had personal and family history of epigastric discomfort or not.The present study was carried out using the method measuring anti-HP IgG in peripheral blood from fingers. Results①Opticaldensity level of G group(0.71±0.29)was significantly different from that of NG group(0.49±0.28)(P<0.005);②Among G group,doctors compared with nurses(P>0.05),endoscopists compared with general practioners(P>0.25),and among three subgroups,who were divided as they had been working in gastroenterology field or endoscopy room for less than 5 years,5～10 years,more than 10 years,no significant differences were found.Conclusions ①Gastroenterology staff has a higher risk of HP infection than other groups in hospitals;②The risk of gastroenterologists or gastroenterology nurses infected by HP would reach the maximum in 5 years;③Using glovers in clinic practice might reduce the incidence of HP infection.