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SLENIUM FROM BEEF IS HIGHLY BIOAVAILABLE AS ASSESSED BY LIVER GLUTATHIONE PEROXIDASE (EC1.11.1.9) ACTIVITY AND TISSUE SELENI

SELENIUM ROM BEEF IS HIGHLY BIOAVAILABLE AS ASSESSED BY LIVER GLUTATHIONE PEROXIDASE(EC1.11.1.9)ACTIVITY AND TISSUE SELENIUM
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摘要 The bioavailability of selenium(Se)from ground beef has been previously found in this laboratory to be greater than that of selenite or selenate when fed to female Fischer 344 rats(B. Shi,J.E.Spallholz,J Am Coil Nutr,13:95 ̄101,1994).In the present study we examined the bioavailability of Se from various commercial portions of beef,the liver,striploin,round, shoulder and brisket.All beef was cooked, freeze-dried,finely powdered and mixed with the other dietary ingredients.The experimental diets were fed to the weanling Fischer 344 rats which had been subjected to dietary depletion of Se for 6 weeks.The bioavailability of Se from the beef diets was compared with that of Se as se lenite or L-seienomethionine(SeMet)added to torula-yeast diets.Each experimental diet contained 0'10mg Se/kg.After 8 weeks of dietary Se repletion,relative activity of liver glutathione peroxidase (EC 1.11.1.9;GSHPx) from the different dietary groups colllpared with that of control animals(100%)was(%):selenite 91,SeMet 122 (P<0.05),liver 108, striploin 105,round 106, shoulder 106,brisket 103.Se recovery in liver was generally highest from SeMet>beef muscle=beef liver>selenite.Muscle tissue deposition of Se was highest from SeMet>beef muscle>selenite=beef liver.In addition, the feeal excretion of Se was lowest from the SeMet dietary group and highest from the selenite dietary group.The experimetal results suggest that all cuts of beef appear to be highly bioavailable sources of dietary Se when compared with selenite or L-SeMet. The bioavailability of selenium(Se)from ground beef has been previously found in this laboratory to be greater than that of selenite or selenate when fed to female Fischer 344 rats(B. Shi,J.E.Spallholz,J Am Coil Nutr,13:95 ̄101,1994).In the present study we examined the bioavailability of Se from various commercial portions of beef,the liver,striploin,round, shoulder and brisket.All beef was cooked, freeze-dried,finely powdered and mixed with the other dietary ingredients.The experimental diets were fed to the weanling Fischer 344 rats which had been subjected to dietary depletion of Se for 6 weeks.The bioavailability of Se from the beef diets was compared with that of Se as se lenite or L-seienomethionine(SeMet)added to torula-yeast diets.Each experimental diet contained 0'10mg Se/kg.After 8 weeks of dietary Se repletion,relative activity of liver glutathione peroxidase (EC 1.11.1.9;GSHPx) from the different dietary groups colllpared with that of control animals(100%)was(%):selenite 91,SeMet 122 (P<0.05),liver 108, striploin 105,round 106, shoulder 106,brisket 103.Se recovery in liver was generally highest from SeMet>beef muscle=beef liver>selenite.Muscle tissue deposition of Se was highest from SeMet>beef muscle>selenite=beef liver.In addition, the feeal excretion of Se was lowest from the SeMet dietary group and highest from the selenite dietary group.The experimetal results suggest that all cuts of beef appear to be highly bioavailable sources of dietary Se when compared with selenite or L-SeMet.
作者 石冰
出处 《Journal of Pharmaceutical Analysis》 CAS 1995年第2期190-190,共1页 药物分析学报(英文版)
关键词 selenium BIOAVAILABILITY BEEF glutathione peroxidase selenite nBri selenium bioavailability beef glutathione peroxidase selenite nBri
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