IHA DGS-COPT F-ELISA试剂盒在血吸虫病监测地区应用价值的研究

STUDIES ON APPLICATION OF IHA、DGS-COPT AND F-ELISA KIT IN SCHISTOSOMIASIS CONTROLLED AREAS

本文比较了IHA、DGS-COPT、快速ELISA试剂盒在血吸虫病监测地区应用价值的研究.共检测1085份血清.3法对检测对象A的阳性检出率依次为75.86%、65.52%、34.48%,敏感性以IHA最高,快速ELISA试剂盒最低,DGS-COPT与IHA的敏感性无显著差异(X^2=0.74,P>0.05).3法特异性无显著差异(X^2=0.24,P>0.05).IHA有一定的远期疗效考核价值,DGS-COPT有近、远期疗效考核价值,但快速ELISA试剂盒尚不能证明有较肯定的现场应用价值.

IHA、DGS-COPT and F-ELISA kit were used for examination of 1 085 serai samples in schistosomiasis controlled areas. With samples of 29 positive stool hatching subjects,the positive rate in IHA、DGS-COPT and F-ELISA kit were 75. 86%、65.52% and 34. 48% respectively. The sensitivity was highest by using IHA and lowest by F-ELISA kit. There was neither obvious difference between the sensitivity of DGS-COPT and IHA(x2 = 0. 74, P>0. 05) nor obvious difference in specificity between these three methods(x2= 0. 24, P>0. 05). The result showed that IHA had certain value for observation of therapeutic effect of drugs in long terms after treatment while DGS-COPT had value for observation of therapeutic effect in both short and long terms. The value of F-ELISA kit method in field use was not definit by the meantime.