血吸虫性结肠肉芽肿病变的扫描电镜观察

OBSERVATION OF COLONZC GRANULOMATOUS LESTION OF SCHISTOSOMIASIS BY SEM

以扫描电镜观察了血吸虫性结肠肉芽肿病变.结合光镜检查和透射电镜观察结果,综合认为,本病变的主要特征之一是粘膜上皮细胞的高度增生,兼有某些瘤性改变,为防止病变的进一步发展,应及早给予有效的内外科治疗.扫描电镜下同时发现,隐窝之间具有绳索样的纤维性增生,认为这是本病变的特征性表现,具有诊断价值.

Normal dogs were infected with 300 cercariae of S. Japonicum every 3 months for 3 times. Two years later,5 infected dogs,which had obvious pathological changes-colonic gran-ulomatous lesion,and 2 normal dogs as control were chosen to make pathological sampling under anesthesia,and also observed under SEM. The result showed that there was obvious proliferation of epithelial cells of colonic mucosa accompanied by some characteristics of car-cinomatous change. The SEM observation the previous microscopic examination and the TEM observation all suggest that those with obvious proliferation in granulomatow lesion should be given surgerical as well as medical treatment as early as posible for prevention of malignant change.