摘要
In order to study the effects of Herba Dracocephali (HD) in treating coronary heart disease(CHD) and antiperoxidative damage. 40 patients of CHD were treated with HD and the changes ot plasma su-peroxide dismutase (SOD) , lipid peroxide (LPO) , thromboxane B2 (TXB2) and 6-keto-prostaglandin F1 (6-keto-PGF1 ) as well as platelet LPO (PL-LPO) , SOD (PL-SOD) and selenium-glutathion peroxidase (SGP)were measured before and after treatment. Results showed that TXB2 , LPO and PL-LPO increased, whileSOD, PL-SOD decreased signiticantly in patients. After treatment by HD, the TXB2 , LPO, PL-LPO loweredand 6-keto-PGF1 , SOD, PL-SOD and SGP elevated obviotjsly. Electron microscopy showed that the ultra-structore of platelets improved and the activity ot adenylate cyclase increased markedly. The results suggest-ed that HD is a traditional Chinese herbal antioxidant and is hopeful tor treating CHD.
In order to study the effects of Herba Dracocephali (HD) in treating coronary heart disease(CHD) and antiperoxidative damage. 40 patients of CHD were treated with HD and the changes ot plasma su-peroxide dismutase (SOD) , lipid peroxide (LPO) , thromboxane B2 (TXB2) and 6-keto-prostaglandin F1 (6-keto-PGF1 ) as well as platelet LPO (PL-LPO) , SOD (PL-SOD) and selenium-glutathion peroxidase (SGP)were measured before and after treatment. Results showed that TXB2 , LPO and PL-LPO increased, whileSOD, PL-SOD decreased signiticantly in patients. After treatment by HD, the TXB2 , LPO, PL-LPO loweredand 6-keto-PGF1 , SOD, PL-SOD and SGP elevated obviotjsly. Electron microscopy showed that the ultra-structore of platelets improved and the activity ot adenylate cyclase increased markedly. The results suggest-ed that HD is a traditional Chinese herbal antioxidant and is hopeful tor treating CHD.
