AgNOR染色对甲状腺良、恶性病变诊断价值的研究

EVALUATION OF AgNORs IN THE DIAGONOSTICS OF BENIGN AND MALIGNANT THYROID TUMOR

本文应用ＡｇＮＯＲ染色技术对７３例甲状腺良恶性病变石蜡切片核仁组成区变化进行观察，其中包括亚急性甲状腺炎５例、腺瘤２５例、结节性甲状腺肿７例、甲状腺癌３６例，结果表明亚急性甲状腺炎、腺瘤、结节性甲状腺肿，细胞核内的ＡｇＮＯＲ颗粒均数及形态与甲状腺癌的均数及形态比较有显著性差异（Ｐ＜０．０１）。我们认为此方法对于区别甲状腺良、恶性病变有一定参考价值。

cases of thyroid lesion, including 5 subacute thyroiditis, 25 adenoma, 7 nodular goiter and 36 carcinoma were studied by using of agyrophil method for nuclear orgonizer regions (NORs). It was found that there was a significant difference (P<0.01) of the mean count and shape of AgNORs between carcinoma and other thyroid lesions. This technique can offer certain help to differentiate malignant and benign thyroid tumors.