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环丙沙星、氧氟沙星、依诺沙星等对小鼠单次腹腔注射产生肝损伤作用程度比较 被引量:1

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摘要 在对新氟喹诺酮类抗生素小鼠腹腔注射急性毒性试验中发现:这类药在低于1/2~1/4 LD<sub>50</sub>剂量作用下,能引起肝脏重度畸型、粘连。该作用在单次给药后15~20天出现,易被试验操作者忽视。小鼠外观活动无异常。
出处 《四川生理科学杂志》 1995年第Z1期76-76,共1页 Sichuan Journal of Physiological Sciences
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  • 1魏东,李振华,张乃生.氟喹诺酮类药物的不良反应[J].动物医学进展,2006,27(7):105-107. 被引量:23
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