乳腺癌患者头发中自由基的ESR研究

THE ESR-SP STUDY FROM THE PATIENTS WITH BREAST CANCER

近３年来，作者利用电子自旋共振波谱技术（ＥＳＲ－ＳＰ），共检测了１０２３例乳腺疾病患者的头发标本。其中乳腺癌２７８例，乳腺良性疾病７４５例，所检头发标本均取自后枕部。１０００个正常人群作为对照。结果表明ＦＳＲ－ＳＰ值对乳腺癌、乳腺良性疾病和对照人群分别为１．７５ｍｗ，２．４２ｍｗ和２．４９ｍｗ，Ｐ值乳腺癌和乳腺良性疾病小于０．０１。作者认为该方法是早期诊断乳腺癌的手段之一。

he ESR-SP(Electron Spin Resonace-Saturation Power)from human hair of 1023 patients withbreast diseases including malignancies and benign diseases has been studied for the recent 3 years.Of them,breast malignancies were 278 cases and benigns were 745. All the hair was from occipital part of the skulland it was processed and analized in the spectrum instrument was which made in Japan.The control samples were from 1000 helthy populations.We found that the ESR-SP was 1.75 mw,2.42 mw and 2.49 mw respectively for breast malignancies,benign diseases and control. The P Value between malignancies and benign diseases was less than 0.01and there was significant difference. The explanations for this was that the free radicals from malignancies was lower because they were inhibited.This was a very useful test for the early diagnosis of breast cancer.