摘要
Point mutation is an important molecular mechanism leading to human geneticdiseases and remains one of the focal areas of research in gene diagnosis. This notereports a simple and rapid method for the detection of known mutant phenylketonuria(PKU)alleles-Multiplex Allele-specific Polymerase Chain Reaction (MASPCR) whichcan identify several point mutations at the same time.
基金
Project sponsored by China Medical Board (CMB)
National 863 High Technology and Natural Science Foundation.
