摘要
The large protein of the hepatitis B virus (HBV) envelope was subdivided intothe preSl region with 108-115 amino acids, the preS2 region with 55 amino acidsand the S region with 226 amino acids. It was believed that the preSl region cotainedthe hepatocyte attachment sites of the virus as well as multiple highly immunogenicT-cell and B-cell epitopes. The antibody response to the preSl peptide was also oneof the most important serological markers of HBV infection.