摘要
The study was prospective, randomized and controlled. It includes 3 parts: (1) clinical study of hyaluronidase (HD) on cervical ripening; (2) action mechanism of HD (experimental study); and (3) effect of cervix collagen on cervical dilatation in term labor. According to the results of preliminary study, HD was selected as ripening agent, its dosage and administration method were investigated previously.