摘要
Ⅷ C and ⅧR: Ag were measured in 24 mothers of patients with hemophilia A in present studies.The rate of detecting hemophilia A carrier by using these methods was more than 90%.There are 10% mistake rate reported by other investigatoro in diagnosis of hemophilia A carrier based on the Ⅷ: C and ⅧR: Ag determination. Although these method is less precise than that of gene diagnosis in detecting hemophilia A carrier, the former is much simple and practicable. Conditionally, the gene diaguosis is not currently available in this country.The measurement of Ⅷ: C and ⅧR:Ag is a good screening method with high detecting rate for carrier detection.
Ⅷ C and ⅧR: Ag were measured in 24 mothers of patients with hemophilia A in present studies.The rate of detecting hemophilia A carrier by using these methods was more than 90%.There are 10% mistake rate reported by other investigatoro in diagnosis of hemophilia A carrier based on the Ⅷ: C and ⅧR: Ag determination. Although these method is less precise than that of gene diagnosis in detecting hemophilia A carrier, the former is much simple and practicable. Conditionally, the gene diaguosis is not currently available in this country.The measurement of Ⅷ: C and ⅧR:Ag is a good screening method with high detecting rate for carrier detection.