摘要
用放射免疫法测定了２０例高原肺水肿（ＨＡＰＥ）患者血清内源性洋地黄样因子（ＥＤＦ）浓度，并与１４例刚入高原健康人对比，结果表明：多数（１５／２０）患者血清ＥＤＦ浓度明显增高（Ｐ＜０．０５），少数患者（５／２０）明显降低（Ｐ＜０．０５）而保持平原值水平；ＥＤＦ浓度与ＰａＯ＿２、左心功能的敏感指标ＰＥＰ／ＬＶＥＴ比值呈明显负相关。对其在ＨＡＰＥ的发生发展中的作用进行了初步探讨。
etermination of serum endogenous digitalis─Like
factor(EDF) concentration was carriedout in 20 patients with high
altitude Pulmonary edema(HAPE)by radioimmunoassay in altitude3658m.
The results showed that concentration of serum EDF in patients with
HAPE was signifi-cantly rise(15/20)or lower(5/20)than in mormal
subjects just getted into altitude 3 658m(P<0.05～0.01).The lowering
of serum EDF concentration was signifiicantly negatively
correlatedwith the severity of heart function,r=-0.6832,P<0. 01,and
relationship of EDF and their ef-fects in pathogenesis and monitoring
of HAPE are further discussed and evaluated.
出处
《高原医学杂志》
CAS
1994年第4期34-37,共4页
Journal of High Altitude Medicine
关键词
高原肺水肿
内源性洋地黄样因子
放射免疫分析法
high altitude
pulmonary edema
endogenous digitalis─like factor
radioimmunoassay.
