41例高红症的血液学指标及相关因素的分析

ANALYSIS OF THE HEMOTOLOGICAL LNDUXES WITH THEIR CORRELAT IONAL FACTORS iN 41 CASES OF PATIENTS WITH HIGH ALTITUDE POLYCYTHEMIA

本文对４１例高红症患者，测定了血液流变学、血小板数量和粘附率、体外血栓形成、凝血和纤溶等项目，并对体外血检形成大小、与Ｈｃｔ．ηｂ．ηＲ．ηｐ进行了相关的分析。结果表明：高红症患者不仅具有典型高粘滞综合征的表现，且可导致血凝、纤溶、血小板数与质的改变，有消耗性凝血障碍。体外血栓形成与Ｈｃｔ．ηｂ呈负相关、与Ｐｃ、Ｆｂ呈正相关。虽然Ｈｃｔ高、血液粘度大，但由于Ｆｂ、Ｐｃ减低、纤溶增强、不利血栓形成，因而高红症患者较少发生大血管血栓性疾患（脑血管和冠状Ａ），这与临床和病理报告结果是一致的。

he induxes of blood rheology,platelet count and platelet adherent rate ,external thrombo- sis,blood coagulation ,fibrinolysis and so on were measured in 41 cases of patients with high alti-tude polycythemia(HAPC )and the correlational analysis of the size of the external thrombosiswith Hct,ηb,ηr,ηp were made The results showed that the patient of HAPC not only had thetypical manifestations of hyperviscositive syndrome, but also induced coagulation, fibrinolysischanges of platelet number and quality and the obstacle of consumptive coagulation. Externalthrombosis presented negtive correlation with Hct and Hb,but positive correlation with Pc andFb.Though Hct was high blood viscosity was big,but Fb aiid Pc reduced and fibrinolysis enhenced,these were unfavourable to thrombosis,As a result the thrombosis diseases of great vessels,such as cerebrovessel and coronary arteriers, less occur,it showsudifference with the results ofclinical and pathological reports.