摘要
在海拔４０８０ｍ地区对５１例高原红细胞增多症患者进行了超氧化物岐化酶（ＳＯＤ）和过氧化脂质（ＬＰＯ）的测定，并与同一海拔健康人进行了对比分析。结果表明：高原红细胞增多症患者ＳＯＤ活性降低（Ｐ＜０．０１）、ＬＰＯ含量增加（Ｐ＜０．０１）。说明高原红细胞增多症患者存在有明显的自由基代谢失衡，这可能是他们体内组织的结构和功能受损伤的重要原因之一，文章对高原红细胞增多症病人体内自由基代谢失衡的原因进行了初步探讨。
uperoxide
dismutase(SOD)and lipid peroxide(LPO)of 51 cases with high altitude
poly-cythemia(HAPC)at 4 080m were measured and were contrasted with
healthy persons at thesame altitude. The results showed that SOD
activity of red blood cells was lowered(P<0. 01)andserum LPO was
increased(P<0.01).It indicated that patients with HAPC had the
imbalance ofmetabolis in free radical and it might be one of
impoatant factors that the structure and functionof organization in
organism were destroied.the reasons were discussed in this paper.
出处
《高原医学杂志》
CAS
1994年第2期15-16,共2页
Journal of High Altitude Medicine
