21及18三体综合征的产前超声筛查

Analysis of prenatal sonography in screening Down syndrome and trisomy 18

目的 对 2 1及 18三体综合征胎儿的超声声像图特征和超声筛查的价值进行评估。方法 对 2 2例证实为 2 1三体综合征及 8例证实为 18三体胎儿的产前超声声像图进行回顾性分析。结果 产前超声对 2 1三体综合征的检出率为64 % ,对 18三体综合征的检出率为 89%。结论 超声是产前筛查 2 1及 18三体综合征的一项实用而有效的方法。

Objective To assess the effectiveness of sonographic screening and discuss sonographic characteristics of Down syndrome and trisomy 18. Methods The subjects were recruited from pregnant women undergoing prenatal sonographic examinations and subsequently proven to be Down syndrome and trisomy 18 by genetic results. Results The results of ultrasound findings in 22 cases confirmed as Down syndrome and 8 cases confirmed as trisomy 18 were retrospectively reviewed. Conclusion Fetal sonography is a practical and effective prenatal screening method for detecting Down syndrome and trisomy 18.