绵阳地区幽门螺杆菌抗原检测血清特异性抗体与上海抗原的对比研究

THE STUDY ON SERUM SPECIFIC ANTIBODY ABOUT HP ANTIGER IN MIANYANG REGION COMPARED WITH SHANGHAI REGION

应用酶联免疫法（ＥＬＩＳＡ）对经胃镜检查的１２２例胃疾病和１０例正常人血清幽门螺杆菌（ＨＰ）抗体ＩｇＧ进行测定，同时与Ｗｉｔｈｉｎ－Ｓｔａｎｙ银染法和尿素酶试验（ＣＰＵＴ）作出比较，并同上海抗原对照检测，结果显示，ＥＬＩＳＡ法检出率最高（７２．７％）；本地区ＨＰ抗原检测血清抗ＨＰ抗体９６例阳性中，上海有１１例未检出，提示ＨＰ菌０株在不同地区可能存在抗原性差异。

The serum HP IgG had been tested by Enzyme-linked immuno assay(ELISA) for 122cases gastricdisease and 10 cases normal people by gastricscope diagnosis. It was also com-pared with warthin-starry sliver staining method and ureaenzyme method.HP antiger wastested in Mianyang and compared with Shanghai.The results showed the rate of ELISA isthe highest(72.7%).96 cases were positive with HP antiger tested serum HP antibody in Mi-anyang and 11 cases were negative in Shanghai.The study suggested HP has specific differ-ence in different region.