摘要
大量研究表明,鼻咽癌与EB病毒有关。通过对98例鼻咽癌组织的切片革兰氏染色L型检查、电镜和L型抗体免疫组化染色等研究,发现鼻咽癌组织中细菌L型亦甚常见,切片革兰氏染色有78例查见细菌L型,其阳性率为79.6%;免疫细化染色L型抗原检出阳性率为62.2%,电镜不仅在细胞间质见到细菌L型,而且在癌细胞、巨噬胞细等细胞胞质内也见到细菌L型。提示,细菌L型与鼻咽癌关系十分密切,很可能是鼻咽癌致癌因子之一。
The
nasopharyneal carcinoma have repeateding been shown to beclosely associated with
Epstein-Barr virus in the documents.In thisarticle,98 cases of nasopharyngeal carcinoma were
examined with Gramstaining, electron microscope examination and immunohisto che
micalstaining.It was found that the infecnion of the bacterial L-forms innasopbaryngeal
carcinoma also very ordinary was discovered. Tbe positiverate of bacterial L-forms was 79.6%
for Gram staining, and was 62.2% inimmunohistochemical staining. Bacterial L-forms were also
observed inthe carcinoma tissues through transmission electromicroscopy. Thebacterial
L-forms not only have the ability to distribute themselves intothe tissue interspace,but can also
intrude oneself into such cell substancesas carcinoma cell,macrophage,etc.It is suggested that
tbe infection ofbacterial L-forms in neoplasm tissues is correlated with
nasopharyngealcarcinoma,and may be direct factor leading to the
nasopharyngealcarcinoma.
出处
《中国微生态学杂志》
CAS
CSCD
1994年第3期13-17,共5页
Chinese Journal of Microecology
关键词
鼻咽癌
细菌L型
Nasopharyngeal carcinoma Bacterial L-forms